comparison of sedative effect of remifentanil with propofol in senile cataract surgery under retrobulbar block

نویسندگان

مهزاد علیمیان

mahzad alimian, farnad imani, mahmoudreza alebouyeh behrouz zaman, alirezqa siamdoust, reza tarjoman استادیار بیهوشی، دانشگاه علوم پزشکی تهران، بیمارستان حضرت رسول اکرم (ص) فرناد ایمانی

دانشیار بیهوشی، مدیر گروه بیهوشی دانشگاه علوم پزشکی تهران بیمارستان حضرت رسول اکرم (ص) محمودرضا آل بویه

استادیار بیهوشی، دانشگاه علوم پزشکی تهران، بیمارستان حضرت رسول اکرم (ص) بهروز زمان

استادیار بیهوشی، دانشگاه علوم پزشکی تهران، بیمارستان حضرت رسول اکرم (ص) علیرضا صیام دوست

چکیده

background: because general anesthesia is not a good choice in elderly asa>ii patients candidate for cataract surgery performored by ophthalmology residents and lack of cooperation in these patients, sedative effect and hemodynamic status and side effects of two drugs, remifentanil & propofol  are compared.   methods : in a randomized clinical trial on 60 patients candidate for cataract surgery which were divided in two group each containing 30 patients were compared. in group a (remifentanil group), patients were sedated with a bolus dose of 0.5 µg/kg within 1 minute , and maintenance dose of 0.05 µg/kg/min. in group b ( propofol  group) ,  patients were sedated with a bolus dose of 0.25 µg/kg, and maintenance dose of 25 µg/kg/min. after retrobulbar block was performored for all the patients by residents. hemodynamic responses, including  hr , dbp , sbp  and o2sat and sedation level according to moaa/ss  were measured . modified observers assessment of awareness/sedation scale   =   moaa/ss              results:  sedation was deeper in  group a  (remifentanil ) measured in all times after block and were statistically meaningful (p<0.05) .the heart rate was  reduced in  group a after 20 minutes after block and were statistically meaningful ( p<0.05). 7 cases  in group a ( remifentanil ) had  nausea after drug administration  (p=0.011). conclusion:  remifentanil can induce high level of sedation for patients compare to propofol. but nausea could be troublesome and in this point propofol has less adverse effect.

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بیهوشی و درد

جلد ۲، شماره ۷، صفحات ۸۱-۰

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